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ΕΡΕΥΝΗΤΙΚΑ ΕΝΔΙΑΦΕΡΟΝΤΑ

Η ομάδα του εργαστηρίου μας δραστηριοποιείται ιδιαιτέρως στον τομέα της έρευνας των παιδιατρικών λοιμώξεων. Συγκεκριμένα, τα ερευνητικά μας ενδιαφέροντα εστιάζονται στη μοριακή επιδημιολογία παθογόνων μικροοργανισμών συμπεριλαμβανομένων βακτηρίων (S. pyogenes, S. pneumoniae) και ιών (Rotavirus, Enterovirus, Parechovirus, SARS-CoV-2, RSV) καθώς και στην ανοσολογική απόκριση που προκαλούν οι παθογόνοι μικροοργανισμοί και τη συσχέτιση τους με κλινικές εκδηλώσεις.

Παρακάτω ακολουθούν ενδεικτικές βιβλιογραφίες των ερευνητικών μας δραστηριοτήτων:

1. Molecular epidemiology and antimicrobial susceptibility of group A Streptococcus isolated from children in Greece during 2023

2. Comparison οf Immune Responses Through Multiparametric T-Cell Cytokine Expression Profile Between Children with Convalescent COVID-19 or Multisystem Inflammatory Syndrome

3. Clinical and Laboratory Parameters Associated with PICU Admission in Children with Multisystem Inflammatory Syndrome Associated with COVID-19 (MIS-C)

4. Genotyping and Molecular Characterization of VP6 and NSP4 Genes of Unusual Rotavirus Group A Isolated from Children with Acute Gastroenteritis

5. SARS-CoV-2 Seroepidemiology and Antibody Levels in Children during BA.5 Predominance Period

6. Epidemiology of respiratory syncytial virus in hospitalized children before, during, and after the COVID-19 lockdown restriction measures in Greece

7. Comparative Study of T-Cell Repertoires after COVID-19 Immunization with Homologous or Heterologous Vaccine Booster

8. The Soluble Urokinase Plasminogen Activator Receptor as a Severity Biomarker in Children With Acute COVID-19 or Multisystem Inflammatory Syndrome

9. Kinetics of SARS-CoV-2 Spike Antibodies after the Second and Third Dose of the BNT162b2 COVID-19 Vaccine and Association with Epidemiological Characteristics and Breakthrough Infection in a Cohort Study of Healthcare Workers

10. Concurrent Familial Cluster of Acute Post-Streptococcal Glomerulonephritis Due to Group A Streptococcus emm2 Type During the Ongoing European Outbreak (2022-23)

11. Rotavirus epidemiology and genotype distribution in hospitalised children, Greece, 2008 to 2020: A prospective multicentre study

12. Pneumococcal meningitis in Greece: A retrospective serotype surveillance study in the post-PCV13 era (2010-2020)

13. Time of Day of BNT162b2 COVID-19 Immunization Affects Total SARS-CoV-2 Antibody Levels but Not Neutralizing Activity

14. Genetic Variations in Human Parechovirus Type 3 in Infants with Central Nervous System Infection

15. Molecular Epidemiology of Enterovirus in Children with Central Nervous System Infections

16. Characteristics of Streptococcus pneumoniae serotype 19A isolates from children in the pre and post Conjugate Vaccine Era